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Kraig Biocraft Laboratories, Inc. (OTCBB: KBLB)
May 8th, 2008.

 
 Kraig Biocraft Laboratories, Inc. (OTCBB: KBLB)

**Breaking News**

Kraig Biocraft Laboratories, Inc. (OTCBB: KBLB) announced today the renewal and expansion of its Collaborative Research and Intellectual Property Agreement with the University of Notre Dame.  

Please take a moment to review the two NEWS Releases below

<<<Spacer>>>
    Breaking *NEWS* From Kraig Biocraft Labs

Press Release Source: Kraig Biocraft Laboratories, Inc.
Thursday May 8, 6:00 am ET

Kraig Biocraft Laboratories, Inc. Signs Intellectual Property and Collaborative Research Agreement With the University of Notre Dame

Expansion of Kraig's Sponsored Research Within University Laboratories to Include Development of Technical Textiles, Diagnostics and Platform Technologies

LANSING, Mich., May 8, 2008 (PRIME NEWSWIRE) -- Kraig Biocraft Laboratories, Inc. (OTC BB:KBLB.OB - News) announced this morning that the Company has just signed a renewal and expansion of its Collaborative Research and Intellectual Property Agreement with the University of Notre Dame. The agreement provides Kraig with exclusive licensing rights for the products and technology developed pursuant to the collaboration. Additionally, the agreement extends and expands the Company's ongoing research and development program in the University's genetic laboratories.

"The sponsored research program with the University of Notre Dame is a continuing success,'' said Kraig's CEO Kim Thompson, "and has already resulted in two provisional patent filings. Kraig's renewal extends the collaborative research into 2009, and expands the focus of the Company's work to include the development of genetic expression systems. These recombinant DNA technologies have potential applications as pharmaceutical platforms and human diagnostics platforms. Each genetic expression system provides multiple possibilities for highly lucrative opportunities for the Company's technology."

The Company's primary focus will remain on the development of high performance, high tensile strength fibers for the multi-billion dollar technical textile market. However, the collaborative research agreement and university research plan will open up new opportunities for Kraig to develop pharmaceutical and diagnostic applications for its genetic engineering technology. This work will continue in the University under the direction of Dr. Malcolm Fraser, a renowned developer of genetic engineering technologies and a member of Kraig's board of scientific advisors.

Already in 2008, Kraig has been able to announce the filing of a provisional patent application for human diagnostic technologies. The invention was a byproduct of the Company's collaborative research program with the University. ``The new research plan announced today is an acknowledgement by the Company that this technology has broad applications as a platform technology. These platforms can potentially service multiple markets including human and animal diagnostics, pharmaceutical platforms and recombinant polymers,'' said Thompson.

A second provisional patent application was filed by the University earlier this year regarding new gene splicing and genetic engineering technologies. The invention relates to the use of DNA's natural repair mechanisms to facilitate gene splicing. This patent application was also filed pursuant to Kraig's collaborative research agreement.

``We are elated that the successful and productive research and development program with the University of Notre Dame will continue into 2009,'' said Thompson. ``With the new and expanded research plan now in place, we look forward to a fruitful year. Kraig is truly a proud sponsor of scientific research and technological development within the University of Notre Dame. We want to thank the University for this renewal of our agreement, and for the diligent work of the scientists who are helping Kraig to make the future in pharmaceutical and textile technologies.''

Kraig Biocraft Laboratories is a technology company focused on the development of commercially significant high-performance polymers, technical fibers and diverse platform technologies. Based on proprietary genetic engineering technology, Kraig is working to develop and produce polymers and protein-based materials including Spider Silk.

For more information on Kraig Biocraft Laboratories please visit the Company's web site: http://www.KraigLabs.com

An audio interview discussing corporate developments is also available on the website.

The Kraig Biocraft Laboratories, Inc. logo is available at http://www.primenewswire.com/newsroom/prs/?pkgid=4817

Statements in this press release about the Company's future and expectations other than historical facts are ``forward-looking statements.'' These statements are made on the basis of management's current views and assumptions. As a result, there can be no assurance that management's expectations will necessarily come to pass. These forward-looking statements generally can be identified by phrases such as ``believes,'' ``plans,'' ``expects,'' ``anticipates,'' ``efforts,'' ``foresees,'' ``future'', ``forecasts,'' ``estimates'', ``intends,'' ``develop,'' ``researching,'' ``research,'' ``goal,'' ``opportunities,'' ``potential,'' ``possibility,'' ``pursue,'' ``could'', ``should'' or other words or phrases of similar import. Similarly, statements in this release that describe the Company's business strategy, outlook, objectives, plans, intentions, marketing strategies, ongoing research, or goals should all be considered forward-looking statements. All such forward-looking statements are subject to certain risks and uncertainties that could cause actual results to differ materially from those in forward-looking statements. Management cautions that its ability to further its research, and create commercially-viable products and execute on its marketing plans may be affected by the competitive environment, the Company's financial condition and its ability to raise sufficient capital to meet the financial obligations of its business plan and to fund its continuing operations.

Contact:
          Kraig Biocraft Laboratories, Inc.
          Kim Thompson, CEO 
          (517) 336-0807
          info@KraigLabs.com

Source: Kraig Biocraft Laboratories, Inc.
<<<spacer>>><<<Spacer>>>
    About Kraig Biocraft Labs

Kraig Biocraft Laboratories, Inc. ("Kraig""KBLB") is a biotechnology company focused on the development of commercially significant high performance polymers and technical fiber. Based on proprietary genetic engineering technology, Kraig is working to develop and produce polymers and protein-based materials including Spider Silk. The company believes that Spider Silk is a “super fiber” that will have numerous commercial and consumer applications. 

Applications of High Performance Fibers

High performance technical fibers are currently used in a wide variety of military, industrial, and consumer applications requiring superior strength, toughness and flexibility. Kraig investments in genetic research are focused on product development and innovative near term solutions to meet the practical problems of our world. Kraig is sponsoring genetic research at laboratories within the University of Notre Dame to create new polymers for the broad commercial markets that have been waiting for the next evolution of materials. Kraig has also been working with leading universities in the fields of genetics and genetic engineering to develop new varieties of recombinant fibers including spider silks and spider silk analogs.

Kraig has obtained the exclusive right, in its field of research, for the spider silk gene sequences which are at the core of its technology. These genetic sequences were first studied and subsequently patented by Dr. Randy Lewis of the University of Wyoming (Dr. Lewis is a KBLB scientific adviser).  In early 2006, Kraig obtained certain exclusive rights from the University of Wyoming to utilize the spider silk DNA sequences in its field of use.

Genetic Engineering is the means by which KBLB can manipulate DNA to modify and create new biochemical products. At Kraig, the trademark saying is  "The future is made in the laboratory" and that's more than a slogan. It is the company's future, and that of the next generation of materials science that KBLB is making with those genetic sequences. Management at KBLB is focused on the development of high strength materials and industrial polymers by working through collaborative research and licensing agreements in the field of genetics, with leading university laboratories. 
<<<spacer>>>
    What's So Special About Spider Silk?

It is five times as strong as steel, twice as elastic as polyamide fibers
(it can be stretched by 31% without breaking),
it is more elastic than aramid fiber,
it is finer than a human hair,
and lighter than cotton. 


 Life Science and Genetic Technology

Spider Silk is among the strongest fibers produced in nature. Some spider species are capable of producing up to seven different types of silk depending upon the spider's particular need at that time. For example, a spider will use one type of silk to make the structural supports for it web, and another type to wrap its captured pray. Drag line silk, the silk used when a spider is repelling, is of particular commercial interest. This natural polymer is both extremely strong and extremely flexible.

However, spider silk is much less dense than steel; its tensile strength to density ratio is roughly five times higher than that of steel (i.e. it is five times as strong as steel of the same density — as strong as Aramid filaments, such as Twaron or Kevlar.)  In fact, a strand of spider silk long enough to circle the earth would weigh less than 16 ounces (450 g).

  • Dragline silk: Used for the web's outer rim and spokes, as well as for the lifeline. As strong as steel, but much tougher. 
  • Capture-spiral silk: Used for the capturing lines of the web. Sticky, extremely stretchy and tough. 
  • Tubiliform silk: Used for protective egg sacs.  Stiffest silk. 
  • Aciniform silk: Used to wrap and secure freshly captured prey. Two to three times as tough as the other silks. 
  • Minor-ampullate silk: Used for minor, all-purpose applications.
HOW  THEY  DO  IT 

Depending on the species, spiders will have anything from two to eight spinnerets, usually in pairs. The beginning of the gland is rich in thiol and tyrosine groups. After this beginning process, the ampulla acts as a storage sac for the newly created fibers. From there, the spinning duct effectively removes water from the fiber and through fine channels also assists in its formation. Lipid secretions take place just at the end of the distal limb of the duct, and proceeds to the valve. The valve is believed to assist in rejoining broken fibers, acting much in the way of a helical pump.

Unspun silk dope is pulled through silk glands, resulting in a transition from stored gel to final solid fiber. Many species of spider have different glands for different jobs, such as housing and web construction, defense, capturing and detaining prey, mobility and in extreme cases even as food. Thus, different specialized silks have evolved with material properties optimized for their intended use.
a
    The Market and the Applications

a
The DNA research that has been conducted in laboratories around the world over the last 20 years, has paved the way for new products and opened up commercial opportunities that would have been undreamed of a generation ago.

DNA instructs cells in their life processes. Genetic engineering is the means by which that machinery is employed.


Artist Kebes using vector drawing software Structure of spider silk. Inside a typical fiber, one finds crystalline regions separated by amorphous linkages. The crystals are beta-sheets that have assembled together.
Transgenics is the scientific process of decoding the genetic instructions of an organism and applying those instructions to another organism. In that way, bio chemicals and other products can be produced and delivered on an industrial scale.

KBLB is at the forefront of the coming revolution in materials technology.

MODERN APPLICATIONS
 Genetic Engineering, is the key to a brighter future for both consumers and industry.

BIOENGINEERED SPIDER SILKS HAVE TREMENDOUS POTENTIAL IN THE MARKET PLACE FOR HIGH STRENGTH, LIGHT-WEIGHT MATERIALS SUCH AS:
Bulletproof vests, parachute cords, suspension cables, wear-resistant shoes 
and clothing, seat belts, rust-free bumpers for automobiles, 
artificial tendons and ligaments

Scientists have previously suggested that a mere pencil-thick strand of silk 
could actually stop a Boeing 747 in mid flight. 

As with all things having to do with thin reinforced materials, 
the U.S. military has in the past expressed great interest in spider silks. In fact, the U.S. Army funded research into production methods for spider silk, but was unable to replicate the mechanical properties of the fiber as produced in nature. But interest in the new material doesn't stop there. Clothing and fabric companies could also benefit from the discovery as well as medical companies that make stents and other biomedical devices.


    Other Recent News From KBLB

Press Release Source: Kraig Biocraft Laboratories, Inc.
Thursday April 10, 6:00 am ET

Kraig Biocraft Laboratories, Inc. Announces Patent Filing On Human Diagnostics Technology

New Diagnostics Platform Incorporating Antigen Fused Polymers

LANSING, Mich., April 10, 2008 (PRIME NEWSWIRE) -- Kraig Biocraft Laboratories, Inc. (OTC BB:KBLB.OB - News) announced today that a provisional patent application describing a platform for antigen presentation and antibody test kits has been filed listing Dr. Malcolm Fraser, a member of Kraig's Scientific Advisory Board, as the named inventor.

The patent application was filed earlier this year by the University of Notre Dame, where Dr. Fraser heads the University's Laboratory of Molecular Virology.

``The invention describes engineered polymers which incorporate diagnostic antigens,'' explained Dr. Malcolm Fraser. ``The genetically fused polymers can potentially be fashioned into a number of different diagnostic test platforms including serum (blood), salivary, and urine based diagnostics. One of the advantages of a polymer based diagnostic platform is its ability to incorporate multiple antigens into a final product simply by weaving the polymers,'' Fraser continued. ``The result would be a diagnostic tool which could simultaneously screen for several diseases or for other important parameters.''

This is the second patent application of 2008 which was made pursuant to Kraig's sponsored research program at the University of Notre Dame and which is subject to Kraig's intellectual property agreement with the University. That agreement provides for exclusive licensing rights for Kraig sponsored research. It is the first such patent application made pursuant to that program relating to human health.

``This ground breaking technology advances Kraig into the growing field of human and animal diagnostics,'' said company CEO Kim Thompson. ``The tremendous potential of genetically fused polymers for diagnostics can not be ignored,'' continued Thompson. ``Our announcement is a big step toward fulfilling the promise of genetically engineered fibers for diagnostics and human health.''  MORE


Press Release Source: Kraig Biocraft Laboratories, Inc.
Monday April 7, 6:00 am ET

Kraig Biocraft Laboratories, Inc. Announces Patent Filing On Genetic Engineering and Gene Splicing Technology

System for Producing Radically New Fibers and Textiles

LANSING, Mich., April 7, 2008 (PRIME NEWSWIRE) -- Kraig Biocraft Laboratories, Inc. (OTC BB:KBLB.OB - News) announced today that Dr. Malcolm Fraser, a scientific consultant to Kraig, and a member of its Scientific Advisory Board, is the named inventor in a now pending provisional patent application describing a system and methodology for redirecting a cell's natural DNA repair processes to perform site-directed cleavage and targeted genetic insertion. The patent describes applications for producing genetically engineered silk fibers. The patent was filed earlier this year by the University of Notre Dame, where Dr. Fraser heads the University's Laboratory of Molecular Virology.

``This genetic engineering system for site-directed cleavage and insertion takes advantage of the DNA's own repair mechanism to insert our own genetic instructions,'' said Dr. Fraser. ``In one of the most important aspects of the invention, it would be possible to insert genetic instructions for the production of polymers with different properties including elasticity and tensile strength.''

``Such polymers could provide radically new fibers and textiles for a number of industries, including human health applications,'' continued Fraser.

The patent application was made pursuant to Kraig's sponsored research program at the University of Notre Dame and is subject to Kraig's intellectual property agreement with the University. That agreement provides for exclusive licensing rights for Kraig sponsored research.  MORE


Press Release Source: Kraig Biocraft Laboratories, Inc.
Tuesday March 18, 6:00 am ET

Kraig Biocraft Laboratories, Inc. Announces Patent Filing On a New Molecule and 
the Artificial DNA Sequences for Producing the Same

New Composites Designed for High-Performance Fiber Market

LANSING, Mich., March 18, 2008 (PRIME NEWSWIRE) -- Kraig Biocraft Laboratories, Inc. (OTC BB:KBLB.OB - News) announced today that it has filed a provisional patent application describing the invention of a number of protein molecules. Also claimed in the application are the artificial DNA sequences which code for these polymers. The application, filed with the U.S. Patent and Trade Mark office in late February, additionally claims a large number of composite fibers which incorporate one or more of the artificial protein molecules.

"These polymers were specifically designed for use as the primary constituents of high performance fibers. Our goal is to create new composites for use in the rapidly growing technical fibers market,'' said Kim Thompson, Kraig's CEO.

The market for technical fibers was estimated at $92.8 billion in 2007. It is projected to grow to $127 billion by 2010 (an average of 10% growth per year).

"These new polymers and composites were inspired by our continuing work with spider silk DNA," continued Thompson. "What is exciting for the technical fibers industry is the tremendous potential of these polymers to satisfy the growing need for new materials with high strength to weight ratios. We believe that the technology disclosed in our patent application will create the foundation for further advances in the high performance fibers marketplace."

Copies of KBLB's latest financial reports and SEC filings are available on the EDGAR system and on the Company's web site: http://www.KraigLabs.com

The Kraig Biocraft Laboratories, Inc. logo is available at http://www.primenewswire.com/newsroom/prs/?pkgid=4817

Statements in this press release about the company's future and expectations other than historical facts are ``forward-looking statements.'' These statements are made on the basis of management's current views and assumptions. As a result, there can be no assurance that management's expectations will necessarily come to pass. These forward-looking statements generally can be identified by phrases such as ``believes,'' ``plans,'' ``expects,'' ``anticipates,'' ``foresees,'' ``forecasts,'' ``estimates'', ``develops'', ``researching''' ``research,'' ``goal,'' ``potential'' or other words or phrases of similar import. Similarly, statements in this release that describe the Company's business strategy, outlook, objectives, plans, intentions or goals should all be considered forward-looking statements. All such forward-looking statements are subject to certain risks and uncertainties that could cause actual results to differ materially from those in forward-looking statements. Management cautions that its ability to further its research, and create commercially-viable products may be affected by the competitive environment, the Company's financial condition and its ability to raise sufficient capital to meet the financial obligations of its business plan and to fund its continuing operations.

Contact:
          Kraig Biocraft Laboratories, Inc.
          Kim Thompson, CEO 
          (517) 336-0807
         info@KraigLabs.com

Source: Kraig Biocraft Laboratories, Inc.
aa
    Financial Information for KBLB


 

Sector: Basic Materials 
Industry: Synthetics 
Recent Price: 0.37
Estimated Market Cap: 18.53M 
Shares Outstanding: 49.93M 

For a PDF viewable in AdobeReader of the KBLB 10Qsb Report for the period ended 09/30/07, Click Here

For the latest FREE version of Adobe Reader, click on the logo below to be redirected to the Adobe site.


KBLB has no off-balance sheet arrangements. KBLB nor any of its subsidiaries 
is a party to any pending or threatened legal proceedings.

Kraig Biocraft Laboratories, Inc. is represented by the law firm of: Anslow & Jaclin, LLP, 195 Route 9 South, Suite 204, Manalapan , NJ 07726. 
KBLB auditors are: Webb & Company, P.A., 1501 Corporate Drive, Suite 150, Boynton Beach , FL 33426. 
The KBLB transfer agent: Registrar & Transfer Company, 10 Commerce Drive, Cranford, NJ  07016-3572 - (800) 866-1340.
aa
    TO CONTACT KBLB

Kraig Biocraft Laboratories, Inc.
Kim Thompson, CEO
120 North Washington Square, Suite 805, Lansing, Michigan 48933
Telephone: (517) 336-0807 - Email: corporate@KraigLabs.com
Web site: www.kraiglabs.com


120 N. Washington Sq.


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